Slow-release morphine was not more effective than methadone in reducing neonatal abstinence syndrome
نویسندگان
چکیده
منابع مشابه
Neonatal abstinence syndrome after maternal methadone treatment.
Thirty two infants born to mothers taking methadone and 32 matched controls were studied to determine the incidence, timing, and frequency of persistence of withdrawal signs in infants born to maternal methadone users. Twelve (37%) infants received treatment for symptoms of withdrawal. The median length of time from birth to initiation of treatment was 23 hours (range 15-64 hours), the median l...
متن کاملMorphine versus clonidine for neonatal abstinence syndrome.
OBJECTIVE The study goal was to determine whether clonidine treatment of neonatal abstinence syndrome (NAS) would result in a better neurobehavioral performance compared with morphine. METHODS This pilot study prospectively enrolled infants ≥ 35 weeks' gestational age admitted for treatment of NAS. After informed consent was obtained, infants were randomized to receive morphine (0.4 mg/kg per...
متن کاملMaternal methadone dose at delivery and neonatal abstinence syndrome.
OBJECTIVE To estimate the relationship between maternal methadone dose and the incidence of neonatal abstinence syndrome (NAS). STUDY DESIGN We performed a retrospective cohort study of pregnant women treated with methadone for opiate addiction who delivered live-born neonates between 1996 and 2006. Four dose groups, on the basis of total daily methadone dose, were compared (<or=80 mg/d, 81-1...
متن کاملNeonatal abstinence syndrome after methadone or buprenorphine exposure.
BACKGROUND Methadone, a full mu-opioid agonist, is the recommended treatment for opioid dependence during pregnancy. However, prenatal exposure to methadone is associated with a neonatal abstinence syndrome (NAS) characterized by central nervous system hyperirritability and autonomic nervous system dysfunction, which often requires medication and extended hospitalization. Buprenorphine, a parti...
متن کاملNeonatal Abstinence Syndrome
Neonatal abstinence syndrome (NAS) is a result of the sudden discontinuation of fetal exposure to substances that were used or abused by the mother during pregnancy. Withdrawal from licit or illicit substances is becoming more common among neonates in both developed and developing countries. NAS continues to be an important clinical entity throughout much of the world. NAS leads to a constellat...
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ژورنال
عنوان ژورنال: Western Journal of Medicine
سال: 2000
ISSN: 0093-0415
DOI: 10.1136/ewjm.172.1.26